City make a few changes from the weekend fixture against Bristol Rovers, with Tommy Doherty, Alan Gow and Jamie Reid all being named amongst the starters.
Visitors QPR name a strong squad, including Joey Barton in midfield with Richard Dunne making his first competitive squad for Rangers.
Exeter City: Krysiak; Moore-Taylor, Coles, Baldwin, Woodman; Wheeler, Bennett, Doherty, Sercombe; Gow; Reid.
Subs: Pym, Davies, Dawson, O’Flynn, Gosling, Keohane, Parkin.
QPR: Murphy, Simpson, Dunne, Hill, Austin, Yun, Jenas, Barton, Hoilett, Zamora, Faurlin.
Subs: Green, Derry, Johnson, Wright-Phillips, Onuoha, Henry, Ehmer.