Exeter City will face West Bromwich Albion under-21s in the EFL Trophy on Tuesday, November 17 in a 7pm kick-off at St James Park.
City kicked-off their EFL Trophy campaign on Tuesday, September 8 with a 3-2 win over Forest Green Rovers and next face Swindon Town away on Tuesday, October 6.
The top two teams from each will progress to the knockout stages.