Exeter City will host fellow League One side Birmingham City in the Vertu Motors Round of 32.
The draw was made live on Sky Sports on Friday night. City guaranteed a home tie after finishing as winners of Southern Group G with a perfect record of three wins.
City will now face Birmingham City twice at SJP in just a couple weeks, after Tuesday November 28's match in League One.
The tie is due to be played the w/c December 9, with further details and ticket prices to follow!